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An introduction to medicinal chemistry / Graham L. Patrick.

By: Material type: TextTextPublisher: Oxford : Oxford University Press, [2013]Copyright date: ©2013Edition: Fifth editionDescription: xxiii, 789 pages : illustrations (some colour) ; 27 cmContent type:
  • text
Media type:
  • unmediated
Carrier type:
  • volume
ISBN:
  • 0199697396
  • 9780199697397
Subject(s): Additional physical formats: No titleDDC classification:
  • 615.19 23
LOC classification:
  • RS403 .P38 2013
Contents:
1. Drugs and drug targets - an overview -- Part A. Drugs and drug targets - an overview :-- 2. Protein structure and function -- 3. Enzymes: structure and function -- 4. Receptors: structure and function -- 5. Receptors and signal transduction -- Part B. Pharmacodynamics and pharmacokinetic : -- 6. Nucleic acids: structure and function -- 7. Enzymes as drug targets -- 8. Receptors as drug targets -- 9. Nucleic acids as drug targets -- 10. Miscellaneous drug targets -- 11. Pharmacokinetics and related topics -- Part C. Drug discovery, design, and development : -- 12. Drug discovery: finding a lead -- 13. Drug design: optimizing target interactions -- 14. Drug design: optimizing access to the target -- 15. Getting the drug to market -- Part D. Tools of the trade : -- 16. Combinatorial synthesis -- 17. Computers in medicinal chemistry -- 18. Quantitative structure-activity relationships (QSAR) -- Part E. Selected topics in medicinal chemistry : -- 19. Antibacterial agents -- 20. Antiviral agents -- 21. Anticancer agents -- 22. Cholinergics, anticholinergics, and anticholinesterases -- 23. Drugs acting on the adrenergic nervous system -- 24. Opioid analgesics -- 25. Antiulcer agents.
Summary: "An Introduction to Medicinal Chemistry is the leading text for university courses on this subject. Renowned for being a textbook loved equally by both students and lecturers, it presents complete coverage in an accessible and engaging style. The text begins with the essential biochemistry on which an understanding of medicinal chemistry is built, introducing the structure and function of important drug targets. It then explores how drugs interact with the body and the consequences of those reactions. There is a section on general principles and strategies involved in discovering and designing new drugs, and another on useful 'tools of the trade'. The text ends with a contemporary look at specific topics within medicinal chemistry, for example, antiviral and anticancer agents; cholinergics and anticholinesterases; and antiulcer agents." --Publisher's website.
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Includes bibliographical references and index.

1. Drugs and drug targets - an overview -- Part A. Drugs and drug targets - an overview :-- 2. Protein structure and function -- 3. Enzymes: structure and function -- 4. Receptors: structure and function -- 5. Receptors and signal transduction -- Part B. Pharmacodynamics and pharmacokinetic : -- 6. Nucleic acids: structure and function -- 7. Enzymes as drug targets -- 8. Receptors as drug targets -- 9. Nucleic acids as drug targets -- 10. Miscellaneous drug targets -- 11. Pharmacokinetics and related topics -- Part C. Drug discovery, design, and development : -- 12. Drug discovery: finding a lead -- 13. Drug design: optimizing target interactions -- 14. Drug design: optimizing access to the target -- 15. Getting the drug to market -- Part D. Tools of the trade : -- 16. Combinatorial synthesis -- 17. Computers in medicinal chemistry -- 18. Quantitative structure-activity relationships (QSAR) -- Part E. Selected topics in medicinal chemistry : -- 19. Antibacterial agents -- 20. Antiviral agents -- 21. Anticancer agents -- 22. Cholinergics, anticholinergics, and anticholinesterases -- 23. Drugs acting on the adrenergic nervous system -- 24. Opioid analgesics -- 25. Antiulcer agents.

"An Introduction to Medicinal Chemistry is the leading text for university courses on this subject. Renowned for being a textbook loved equally by both students and lecturers, it presents complete coverage in an accessible and engaging style. The text begins with the essential biochemistry on which an understanding of medicinal chemistry is built, introducing the structure and function of important drug targets. It then explores how drugs interact with the body and the consequences of those reactions. There is a section on general principles and strategies involved in discovering and designing new drugs, and another on useful 'tools of the trade'. The text ends with a contemporary look at specific topics within medicinal chemistry, for example, antiviral and anticancer agents; cholinergics and anticholinesterases; and antiulcer agents." --Publisher's website.

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