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The human pain system : experimental and clinical perspectives / Frederick A. Lenz [and others].

By: Material type: TextTextPublisher: Cambridge, U.K. ; New York : Cambridge University Press, 2010Description: x, 638 pages : illustrations (some colour) ; 26 cmContent type:
  • text
Media type:
  • unmediated
Carrier type:
  • volume
ISBN:
  • 0521114527
  • 9780521114523
Subject(s): DDC classification:
  • 616.0472 22
LOC classification:
  • QP451.4 .H86 2010
Contents:
Discovery of the anterolateral system and its role as a pain pathway -- Organization of the central pain pathways -- Physiology of cells of origin of spinal cord and brainstem projections -- Physiology of supraspinal pain, related structures -- Functional brain imaging of acute pain in healthy humans -- Pain modulatory systems -- Peripheral and central mechanisms and manifestations of chronic pain and sensitization -- Functional imaging of chronic pain -- Functional implications of spinal and forebrain procedures for the treatment of chronic pain.
Review: "Pain is a subject of increasing scientific and clinical interest. Studies of non-primate animal models have contributed greatly to our knowledge of pain. Nonetheless, investigators often refer to basic neuroscientific and behavioral studies of humans and non-human primates to emphasize the relevance of their results to human pain. Likewise, the interpretation of human pain studies and clinical observations relies upon understanding the relevant anatomy and physiology as gleaned from animal, and especially primate, research. Here, Lenz, Casey, Jones, and Willis review the neurobiology of nociception in monkeys and pain in humans, to provide a firm basis for understanding the mechanisms of normal and pathological human pain. This book is essential reading for anyone interested in pain research."--BOOK JACKET.
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Includes bibliographical references and index.

Discovery of the anterolateral system and its role as a pain pathway -- Organization of the central pain pathways -- Physiology of cells of origin of spinal cord and brainstem projections -- Physiology of supraspinal pain, related structures -- Functional brain imaging of acute pain in healthy humans -- Pain modulatory systems -- Peripheral and central mechanisms and manifestations of chronic pain and sensitization -- Functional imaging of chronic pain -- Functional implications of spinal and forebrain procedures for the treatment of chronic pain.

"Pain is a subject of increasing scientific and clinical interest. Studies of non-primate animal models have contributed greatly to our knowledge of pain. Nonetheless, investigators often refer to basic neuroscientific and behavioral studies of humans and non-human primates to emphasize the relevance of their results to human pain. Likewise, the interpretation of human pain studies and clinical observations relies upon understanding the relevant anatomy and physiology as gleaned from animal, and especially primate, research. Here, Lenz, Casey, Jones, and Willis review the neurobiology of nociception in monkeys and pain in humans, to provide a firm basis for understanding the mechanisms of normal and pathological human pain. This book is essential reading for anyone interested in pain research."--BOOK JACKET.

Machine converted from AACR2 source record.

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