Biomaterials science : an introduction to materials in medicine /

Biomaterials science : an introduction to materials in medicine / edited by Buddy D. Ratner [and others]. - Second edition. - xii, 851 pages : illustrations ; 29 cm

Includes bibliographical references and index.

Biomaterials science : a multidisciplinary endeavor -- A history of biomaterials -- Properties of materials -- Introduction -- Bulk properties of materials -- Finite element analysis -- Surface properties and surface characterization of materials -- Role of water in biomaterials -- Classes of materials used in medicine -- Introduction -- Polymers -- Silicone biomaterials : history and chemistry -- Medical fibers and biotextiles -- Hydrogels -- Applications of "smart polymers" as biomaterials -- Bioresorbable and bioerodible materials -- Natural materials -- Metals -- Ceramics, glasses, and glass-ceramics -- Pyrolytic carbon for long-term medical implants -- Composites -- Nonfouling surfaces -- Physicochemical surface modification of materials used in medicine -- Textured and porous materials -- Surface-immobilized biomolecules -- Some background concepts -- Background concepts -- The role of adsorbed proteins in tissue response to biomaterials -- Cells and cell injury -- Tissues, the extracellular matrix, and cell-biomaterial interactions -- Mechanical forces on cells -- Host reactions to biomaterials and their evaluation -- Introduction -- Inflammation, wound healing, and the foreign-body response -- Innate and adaptive immunity : the immune response to foreign materials -- The complement system -- Systemic toxicity and hypersensitivity -- Blood coagulation and blood-materials interactions -- Tumorigenesis and biomaterials -- Biofilms, biomaterials, and device-related infections -- Biological testing of biomaterials -- Introduction to testing biomaterials -- In Vitro assessment of tissue compatibility -- In Vivo assessment of tissue compatibility -- Evaluation of blood-materials interactions -- Large animal models in cardiac and vascular biomaterials research and testing -- Microscopy for biomaterials science -- Degradation of materials in the biological environment -- Introduction : degradation of materials in the biological environment -- Chemical and biochemical degradation of polymers -- Degradative effects of the biological environment on metals and ceramics -- Pathological calcification of biomaterials -- Application of materials in medicine, biology, and artificial organs -- Introduction -- Nonthrombogenic treatments and strategies -- Cardiovascular medical devices -- Implantable cardiac assist devices -- Artificial red blood cell substitutes -- Extracorporeal artificial organs -- Orthopedic applications -- Dental implantation -- Adhesives and sealants -- Ophthalmological applications -- Intraocular lens implants : a scientific perspective -- Burn dressings and skin substitutes -- Sutures -- Drug delivery systems -- Bioelectrodes -- Cochlear prostheses -- Biomedical sensors and biosensors -- Diagnostics and biomaterials -- Medical applications of silicones -- Tissue engineering -- Introduction -- Overview of tissue engineering -- Immunoisolation -- Synthetic bioresorbable polymer scaffolds -- Implants, devices, and biomaterials : issues unique to this field -- Introduction -- Sterilization of implants and devices -- Implant and device failure -- Correlation, surfaces and biomaterials science -- Implant retrieval and evaluation -- New products and standards -- Introduction -- Voluntary consensus standards -- Development and regulation of medical products using biomaterials -- Ethical issues in the development of new biomaterials -- Legal aspects of biomaterials -- Perspectives and possibilities in biomaterials science -- Properties of biological fluids -- Properties of soft materials -- Chemical compositions of metals used for implants -- The biomaterials literature. Ch. 1. 1.1. 1.2. 1.3. 1.4. 1.5. Ch. 2. 2.1. 2.2. 2.3. 2.4. 2.5. 2.6. 2.7. 2.8. 2.9. 2.10. 2.11. 2.12. 2.13. 2.14. 2.15. 2.16. Ch. 3. 3.1. 3.2. 3.3. 3.4. 3.5. Ch. 4. 4.1. 4.2. 4.3. 4.4. 4.5. 4.6. 4.7. 4.8. Ch. 5. 5.1. 5.2. 5.3. 5.4. 5.5. 5.6. Ch. 6. 6.1. 6.2. 6.3. 6.4. Ch. 7. 7.1. 7.2. 7.3. 7.4. 7.5. 7.6. 7.7. 7.8. 7.9. 7.10. 7.11. 7.12. 7.13. 7.14. 7.15. 7.16. 7.17. 7.18. 7.19. Ch. 8. 8.1. 8.2. 8.3. 8.4. Ch. 9. 9.1. 9.2. 9.3. 9.4. 9.5. Ch. 10. 10.1. 10.2. 10.3. 10.4. 10.5. Ch. 11. App. A. App. B. App. C. App. D.

"The second edition of this bestselling title presents the most up-to-date comprehensive reviews of all aspects of biomaterials science by providing a balanced, curricular approach to learning biomaterials. An historical perspective of materials engineering principles is integrated with the biological interactions of biomaterials, regulatory and ethical issues and future directions of the field, and a state-of-the-art update of medical and biotechnological applications. From tissue engineering to cochlear prostheses and drug delivery systems, all aspects of this important and growing field are thoroughly addressed. Contributions detailing the principles of cell biology, immunology, and pathology from pre-eminent researchers and practitioners from diverse academic and professional backgrounds have been integrated into this important volume. The chapters focus on the clinical uses of biomaterials as components in implants, devices, and artificial organs and their uses in biotechnology as well as the characterization of the physical, chemical, biochemical and surface properties of these materials.*Over 80 contributors from academia, government and industry.*The most up-to-date comprehensive reviews of all aspects of biomaterials*Endorsed by the Society for Biomaterials*Provides comprehensive coverage of principles and applications of all classes of biomaterials*Integrates concepts of biomaterials science and biological interactions with clinical science and societal issues including law, regulation, and ethics*Discusses successes and failures of biomaterials applications in clinical medicine and the future directions of the field*Cover the broad spectrum of biomaterial compositions including polymers, metals, ceramics, glasses, carbons, natural materials, and composites"--Publisher description.

0125824637 9780125824637

2003027823


Biomedical materials.

R857.M3 / B5735 2004

610.28

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